Blar i forfatter "Bhatta, Laxmi"

Viser treff 1-3 av 3

    • Proteome-wide Mendelian randomization in global biobank meta-analysis reveals multi-ancestry drug targets for common diseases 

      Zhao, Huiling; Rasheed, Humaria; Nøst, Therese Haugdahl; Cho, Yoonsu; Liu, Yi; Bhatta, Laxmi; Bhattacharya, Arjun; Hemani, Gibran; Davey Smith, George; Brumpton, Ben Michael; Zhou, Wei; Neale, Benjamin M.; Gaunt, Tom R.; Zheng, Jie (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-12)
      Proteome-wide Mendelian randomization (MR) shows value in prioritizing drug targets in Europeans but with limited evidence in other ancestries. Here, we present a multi-ancestry proteome-wide MR analysis based on cross-population data from the Global Biobank Meta-analysis Initiative (GBMI). We estimated the putative causal effects of 1,545 proteins on eight diseases in African (32,658) and European ...

    • Survival on antiretroviral treatment among adult HIV-infected patients in Nepal: a retrospective cohort study in far-western Region, 2006–2011 

      Bhatta, Laxmi; Klouman, Elise; Deuba, Keshab; Shrestha, Rachana; Karki, Deepak Kumar; Ekström, Anna Mia; Ahmed, Luai Awad (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Though financial and policy level efforts are made to expand antiretroviral treatment (ART) service free of cost, survival outcome of ART program has not been systematically evaluated in Nepal. This study assesses the mortality rates and determinants among adult HIV-infected patients on ART in Far-western region of Nepal. This retrospective cohort study included 1024 (51.2% men) HIV-infected patients ...

    • Survival pattern and determinants of survival in adult HIV-infected patients on antiretroviral treatment in Far-western Development Region, Nepal 

      Bhatta, Laxmi (Master thesis; Mastergradsoppgave, 2012-12-31)
      Objective: This study explores the survival pattern and its determinants among adult HIV-infected patients on ART. Methods: This retrospective cohort study included 1024 (51.2% were men) HIV-infected patients aged ≥15 years who started ART between May 15, 2006 and May 15, 2011 in 5 ART centres in Nepal. Follow-up time was calculated from the date of ART initiation to date of death or censoring ...